Myelopeptide-2 (MP-2) (C41H57N7O8), with the sequence Leu-Val-Val-Tyr-Pro-Trp, is originally isolated from the supernatant of porcine bone marrow cell culture, and is able to restore the mitogen responsiveness of human T lymphocytes inhibited by conditioned medium from HL-60 leukemia cells or measles virus. The MP-2 recovery effect is connected with its influence on the CD3 and CD4 antigen expression on T lymphocytes. Research results also suggest that the MP-2 involvement in regulatory processes is directed to the maintenance of immune homeostasis. This peptide is perspective to be applied in antitumor and antivirus therapy.

Product information

Molecular Weight: 775.93

Formula: C41H57N7O8

Chemical Name: (2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-3-methylbutanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-3-(1H-indol-2-yl)propanoic acid

Smiles: CC(C)C[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC2=CC=CC=C2N1)C(O)=O

InChiKey: ZQWXARYGPROKDX-LXOXETEGSA-N

InChi: InChI=1S/C41H57N7O8/c1-22(2)18-29(42)36(50)46-35(24(5)6)39(53)47-34(23(3)4)38(52)44-31(19-25-13-15-28(49)16-14-25)40(54)48-17-9-12-33(48)37(51)45-32(41(55)56)21-27-20-26-10-7-8-11-30(26)43-27/h7-8,10-11,13-16,20,22-24,29,31-35,43,49H,9,12,17-19,21,42H2,1-6H3,(H,44,52)(H,45,51)(H,46,50)(H,47,53)(H,55,56)/t29-,31-,32-,33-,34-,35-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.